Calcitonin for bone loss
Calcitonin (kal-si-TOE-nin) sold under the
brand names Calcimar, Cibacalcin, Calsynar, Miacalcin,
Osteocalcin and Salmonine is a medication prescribed for the treatment of Osteoporosis. This medication is also
used to treat hypercalcaemia, Paget's disease and bone metastases.
If you find that
the Bisphosphonate medications such as: Actonel ,
irritate your digestive tract, this drug may be an alternative.
There are two two main forms of this drug: Calcitonin-Human
(kal-si-TOE-nin HYOO-man) which is injectable and
and Calcitonin-Salmon (kal-si-TOE-ninSAM-en) which comes in
both an injectable form and as a nasal spray.
This drug was first purified in 1962
by DH Copp and B. Cheney who then published a report of their work in
Nature. See: Copp DH, Cheney B. Calcitonin-a hormone from the parathyroid
which lowers the calcium-level of the blood. Nature 1962;193:381-2.
Frequently asked questions:
- Exactly what is it?
"Calcitonin is a a 32 amino acid polypeptide hormone that
is produced in humans primarily by the C cells of the thyroid".
according to the Wikipeida Encyclopedia.
- What does this drug do?
This hormonal drug affects calcium and phosphorus metabolism. Its
main effect is on bone. As you know your bones are constantly
being remodeled. Old bone is removed by your osteoclasts cells
and new bone is made by your osteoblasts cells. Calcitonin inhibits
the activity of osteoclasts and it
promotes bone formation by osteoblasts. It also decreases
mineral release and matrix or collagen breakdown in bone.
As a result Calcitonin,
has the effect of increasing bone density and that is why it is
prescribed for the treatment of Osteoporosis.
- What should I discuss with my health care provider
There are a number of things you should discuss with your health care
provider. It is important that you raise these things before the
medication is prescribed.
a. Allergies.Be sure to tell your health care provider
if you have had any allergic reactions to other drugs,
food, chemicals or other substances,
b. Other medications or herbal supplements.
Sometimes medications and herbal remedies can interact with each other.
Be sure you mention all the drugs (both prescription and over the
counter) and herbs that you are currently taking to your health care
provider. This is important since your health care provider might need
to change your dosage depending on what else you are taking.
c. Practice. If you are going to betaking the
injectable form of this drug be sure that you do a practice session in your providers office. If you are
going to be taking the nasal spray form, you want to be sure that you
are aiming the spray correctly. Most health care providers are more than
happy to be sure that you have 'good patient education' for the use of
d. Diet, nutrition. Be sure to discuss your
intake of calcium and Vitamin D with your health care provider if you
are going to take this drug. This is important. For some conditions, you
may be advised to take extra supplements. For other conditions, you may
be advised to follow a low calcium diet. Be sure to discuss your
calcium and Vitamin D intake with your health care provider before you start this medication.
- How should I store this drug?
Keep this prescription out of the reach of children and
store it away from heat and direct light.
Calcitonin-human should not be refrigerated but it should be
stored at a temperature below 77 °F. You should use your prepared
solution within 6 hours.
Store calcitonin-salmon in the refrigerator. Do not put it in
the freezer and keep it from freezing.
As with all medications, do not keep outdated drugs. If your
prescription is outdated, contact your health care provider for a new
- Are there any side effect that I should be aware of? This medication does not often produce negative reactions. Sometimes the nasal spray may cause irritation. If this occurs,
do contact your health care provider.
If you experience skin rash or hives after taking this drug,
contact your health care provider immediately. Sometimes your body may take awhile to adjust to a new
medication. If any of the following occur and continue for awhile,
contact your health care provider to discuss it: Diarrhea; flushing or
redness of face, ears, hands, or feet; loss of appetite; nausea or
vomiting; pain, redness,increased urination frequency or Chills;
dizziness; headache; pressure in chest; stuffy nose; tenderness or
tingling of hands or feet; trouble in breathing; weakness soreness, or
swelling at place of injection or stomach pain. Many people have no
negative reactions to this drug. Just because someone has had a
negative reaction, that does not mean that you will.
BUT If you have rash or hives, do contact your health care provider
immediately since this could be an allergic reaction. As for
any other reaction, contact your health care provider if it does
not go away after a short while.
Important discussion to have with your health care provider
There have been some studies showing that there may be a small increase in the risk of cancer for those taking this drug. Do discuss this with your health care provider - especially if cancer has been a factor in your life or in that of relatives. Your health care provider should be able to review the studies and discuss any risks with you.
In 2013 the Joint Meeting of the Advisory Committee forReproductive Health Drugs and the Drug Safety and Risk Management Advisory Committee issues a long study/report about this drug. You can read it at Calcitonin Salmon for the Treatmentof Postmenopausal Osteoporosis
Click here read about other drug treatments for Osteoporosis,Ostepenia
You can find non-drug treatments at Natural treatments for bone loss