Kyphoplasty research

Kyphoplasty research studies have been published for several years. I hope to present you with an overview of these....and I include the journal information, and in some cases links to the studies, so you can read the originals for your self.  And if you have questions, you will be able to print out relevant parts to bring to your physician.

In 2013 researchers Yang Yimin, Ren Zhiewi, Ma Wei and Rajiv Jah of the Department of Orthopedics, The First Affiliated Hospital of Medical College of Xian Jiaotong University, Xi’an, Shaanxi, ChinaCorresponding Authors: Ren Zhiwei published a review, The Current status of percutaneous vertebroplasty and percutaneous kyphoplasty

If you read no other article this one is worth reading since provides an overview of other published  research on the topic. Kyphoplasty research review

Earlier Kyphoplasty research studies

1."Back Pain, Vertebroplasty, and Kyphoplasty: Treatment of Osteoporotic Vertebral Compression Fractures" by S. Bobo Tanner MD. Journal of Rheumatic Diseases. vol 52;no 2. states, in part:

"Kyphoplasty is the newer of the 2 procedures, and, as such, there are fewer published reports. Outcomes analysis from Liebermann’s series of 30 patients and 70 kyphoplasty procedures showed significant improvement in bodily pain and physical function using SF-36 questionnaire data (8). In a multicenter kyphoplasty study with 340 patients and 376 kyphoplasty procedures, 90% of the patients reported pain relief (12). Another retrospective analysis of 1,439 patients and 2,194 kyphoplasty procedures revealed pain relief in 90% of the patients within 2 weeks of the procedures (12). Other studies have noted that 75% of those patients who obtain pain relief gain it immediately after the procedure, and the remainder of those who will get pain relief experience it within the first 4 weeks after procedure (12).

One of the benefits of kyphoplasty is the restoration of vertebral height....

2. Comparison study: "Minimal invasive stabilization of osteoporotic vertebral fractures: a prospective nonrandomized comparison of vertebroplasty and balloon kyphoplasty." by

Grohs JG, Matzner M, Trieb K, Krepler P. J Spinal Disord Tech. 2005 Jun;18(3):238-4.

"CONCLUSIONS: In nonrecent fractures, the reduction of the kyphotic wedge by balloon kyphoplasty was superior in decreasing pain persisting over a period of 2 years. The ability to improve disability after kyphoplasty was limited to 1 year. In nonrecent fractures, the consequences of age and osteoporosis seem to equalize the effects of of the restored sagittal profile on disability but not on pain."

3. "Treatment of osteoporotic vertebral compression. Explosive interest for vertebroplasty and kyphoplasty" by

Karlsson MK, Hasserius R, Gerdhem P, Obrant KJ, Ohlin A. Lakartidningen. 2005 May 23-29;102(21):1644-6, 1648.

"During the last 15 years, two new treatment strategies have gained worldwide attention in the treatment of osteoporotic vertebral fractures. The exponential increase in the use of percutaneous vertebro- or kyphoplasty has up to now not been supported by scientific sound evidence-based data. There exist no prospective randomised controlled trials (RCT) that support the efficacy of the treatments, not even adequate controlled studies. Instead we have to rely on prospective and retrospective uncontrolled short-term observational studies and case-control studies. These studies consistently indicate that the short-term results after the procedures in the treatment of osteoporotic vertebral fractures are favourable, regarding both pain relief and functional status. However, if a vertebro- or a kyphoplasty produces a better outcome than conservative treatment, and if the long-term results are as favourable as the short-term results in the treatment of osteoporotic vertebral fractures, is currently unknown."

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