Aclasta Osteoporosis information. Aclasta is an Osteoporosis drug distributed in Europe and in Australia. In the United States, Acalsta is distributed under a different name, Reclast. This is the exact same drug as Aclasta. It just has a different name.
Some facts about Aclasta. Aclasta is a form of zolendronic acid which is a bisphosphonate, a drug that slow the rate at which 'old bone' is removed. Aclasta is administered by an infusion in your doctor's office. You go to the office. They set up an IV which brings Aclasta into your vein. Then you go home. Done. No daily or weekly pills to remember. Many patients prefer this medication because it is a once a year treatment. Make an appointment, go to your doctor's office, have your infusion and then you are done til next year.
Osteoporosis treatment with Aclasta (Reclast) appeals to those of use who prefer not to be taking daily or weekly pills. There is nothing to remember with this drug! (And most doctors' office staff are willing to keep track of your treatment date and they will call you when it is time for you to make an appointment and come in for your annual infusion.
OK. If you are considering Aclasta for treating your Osteoporosis, you probably want to know a bit more....so read on.
Novartis, one of the largest pharmaceutical companies in the world, is the company that makes Aclasta. They are the ones who developed the drug and did the necessary research studies.
After one study, The Pivotal Fracture Trial, showed that Aclasta both increased bone strength and reduced fractures of the hip, spine and other areas such as wrists, arms, legs and/or ribs, the drug was approved for use by those with documented bone loss.
Note: These studies showed that Aclasta appeared to be effective in reducing fractures, which is the real reason why anyone would treat Osteoporosis. No one wants a fracture because their bones have become thinner, weaker because of age or other things. (See: Causes of Osteoporosis, Osteopenia )
Back when Aclasta was approved, it was the only treatment that was shown to reduce fractures at ALL the key sites where Osteoporosis fractures usually occur: hips, spine, wrists, arms, legs and ribs.
And for those concerned about the small spinal fractures that cause dowagers humps, (back hump) the New England Journal of Medicine reported in May 2007 that a study involving more than 7,700 women, showed that treatment with Aclasta reduced the risk of spinal fractures by 70% AND it reduced hip fractures by 41%.
The reduction in spinal fractures for the three years of the study was as follows: 60% reduction in year one; 71% in year two and 70% in year three. Those are significant numbers! -- especially when we consider that bone loss in the spine usually leads to kyphosis (or dowagers hump) - an unsightly and often debilitating condition.
A spokesperson for Novatis, the company manufacturing Aclasta, states in their Aclasta Osteoporosis information that the drug:
"has shown significant efficacy in protecting women against fractures in all the common osteoporotic fracture sites, while demonstrating a favorable safety profile. It is our hope that this innovative once-yearly dosing regimen will have a positive impact on the management of this potentially devastating condition."
Also, in the same Aclasta Osteoporosis information, Novartis says that Aclasta "is indicated for treatment of osteoporosis in postmenopausal women. In patients with a recent low-trauma hip fracture".. and that this drug.. "reduces the incidence of new clinical fractures".
If you are considering getting this annual drug infusion, you may be interested in knowing that Aclasta is:
Other advantages of Aclasta. Many in the health care community believe that once a year infusions are the helpful for patients because they offer a remedy for the inconvenience of daily, weekly or monthly Osteoporosis medications. Also annual infusions eliminate one of the main problems of daily or monthly medications - that many people just stop taking their prescribed medication! (The failure to take medication is called 'non-compliance' by the medical community and it has been shown that Osteoporosis medication non-compliance with daily or weekly pills is high. Aclasta reduces the non-compliance rate.)
Aclasta Osteoporosis information: Side Effects. Note: Since this drug is sold under various names in different countries, these same side effects apply to its other forms such as, Reclast. (In fact, if you live in the United States, the Novartis site will direct you to a page about Reclast, not Aclasta)
Since this is a bisphosphonate drug Novartis is careful to mention in their Aclasta Osteoporosis information that is a possibility of developing Osetonecrosis . The company also states in its Aclasta information that:
"Disturbances of mineral metabolism must be treated before starting therapy. Patients must be adequately supplemented with calcium and vitamin D. A single dose of Aclasta should not exceed 5 mg and infusion time should be no less than 15 minutes."
Serious side effects: A study published in March of 2013, showed a serious side effect with this drug: Acute kidney injury. If you want to read a summary of that study click this link to it: Journal of Oncology Practice.
If you want to read about other potential side effects as well as a list of medical conditions that would preclude you from using this drug go to: Aclasta Information: Reclast side effects
There is even more Aclasta Osteoporosis information, including some you can print out to take with your to your visit with your health care provider, at: Aclasta, Reclast Research Studies
If you have used this drug and want to leave a comment about your experience on this Aclasta Osteoporosis information page, please scroll down and use the form provided. Thanks.
If you are interested in learning about the natural treatments for building stronger bones, go to Natural Osteopenia, Osteoporosis Treatments
NOTE: This web site offers science based information, such as the Aclasta information given above. The web site does not offer medical advice at any time. For medical advice you need to consult your licensed medical practitioner.
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Jean in Adelaide, South Australia Not rated yet
On 23 January 2018 I had my first infusion of Aclasta. I felt fine for around 15 hours afterwards and then developed the flu like symptoms I was warned …
Aclasta reaction Not rated yet
I had aclasta on a Tuesday afternoon that night I started shaking and felt like I had been transported to the Antartic. Muscle pain in the back and legs …