Aclasta Osteoporosis information

Aclasta Osteoporosis information. Aclasta is the name of an Osteoporosis drug sold in Europe and Australia. In the United States this drug is distributed under the name Reclast. ( See: Reclast )

Aclasta is a form of zoledronic acid and you take it by getting an an infusion of the drug in your doctor's office. Many patients like getting this Osteoporosis medication  because they only have to receive treatment once a year.  (There is no need to remember daily or weekly pills.) You go to your doctor's office once a year, have your infusion and then you are done til next year.

Osteoporosis treatment with Aclasta (Reclast) appeals to those who like not having to remember daily or weekly pills. There is nothing to remember with this drug! Most doctors' office staff are more than willing to keep track and give you a call when it is time for you to come in for your annual infusion

But if you are considering Aclasta, you want to know a bit more about the drug.  I assume that you are especially interested in knowing if there are things about it that could pose problems for you. 

Who makes Aclasta ?

Novartis,  one of the largest pharmaceutical companies in the world, is the company that makes Aclasta.   They developed the drug and did the necessary studies on it.  After study called The Pivotal Fracture Trial showed that Aclasta increased bone strength and it reduced fractures of the hip, spine and other areas such as people's wrists, arms, legs and/or ribs,  Aclasta was approved for use.

Please Note: At the time it was claimed that this treatment is the only treatment that was shown to reduce fractures at ALL the key sites where Osteoporosic fractures usually occur: hips, spine, wrists, arms, legs and ribs. This was important.  Aclasta actually appeared to be effective in reducing fractures, the real reason why anyone would undergo treatment for Osteoporosis.

In addition, for those concerned about the small spinal fractures that can cause dowagers humps, you'll want to know that in May 2007 the New England Journal of Medicine reported that in a study involving more than 7,700 women, it was shown that treatment with this drug reduced the risk of spinal fractures by 70%  (as well as reducing hip fractures by 41%.) 

The reduction in spinal fractures for the three years of the study was as follows: 60% reduction in year one; 71% in year two and 70% in year three. Those are significant numbers! - especially when we consider that bone loss in the spine usually lead to kyphosis (or dowagers hump)  - a difficult and unsightly condition. 

More Aclasta Osteoporosis information:

A spokesperson for Novatis reported in their Aclasta Osteoporosis information that this drug: "has shown significant efficacy in protecting women against fractures in all the common osteoporotic fracture sites, while demonstrating a favorable safety profile, It is our hope that this innovative once-yearly dosing regimen will have a positive impact on the management of this potentially devastating condition." 

Novartis also states in its Aclasta Osteoporosis information that the medication: "is indicated for treatment of osteoporosis in postmenopausal women. In patients with a recent low-trauma hip fracture".. the drug.. "reduces the incidence of new clinical fractures".   

More Aclasta Osteoporosis information

If you are considering getting this annual infusion, you may be interested in knowing that Aclasta is:

  •  also  "indicated for treatment of osteoporosis in men at increased risk of fracture, including those with a recent low-trauma hip fracture."
  • "indicated for treatment of osteoporosis associated with long-term systemic glucocorticoid therapy in postmenopausal women and in men with increased risk of fracture".
  • and finally, "Aclasta is indicated for the treatment of Paget's disease of the bone."

Many in the health care community believe that once a year infusions are the helpful for patients because they offer a remedy for the inconvenience of daily, weekly or monthly Osteoporosis medications.  Also annual infusions eliminate one of the main problems of daily or  monthly medications - that many people just stop taking their prescribed medication! (The failure to take medication is called 'non-compliance' by the medical community and it has been shown that Osteoporosis medication non-compliance with daily or weekly pills is high.)

Alcasta Osteoporosis information: Side effects

Aclasta Osteoporosis information: side effects Since this drug is sold under various names in different countries, the same side effects apply to its other form:  Reclast.  (In fact, if you live in the United States, the Novartis site will direct you to a  page about Reclast.)

Novartis is careful to mention in their Aclasta Osteoporosis information the possibility of developing Osetonecrosis with Aclasta since it is a bisphosphonate drug. . The company also states in its Aclasta information that:

"Disturbances of mineral metabolism must be treated before starting therapy. Patients must be adequately supplemented with calcium and vitamin D. A single dose of Aclasta should not exceed 5 mg and infusion time should be no less than 15 minutes."

Serious side effects: A study published in March of 2013, showed a more serious side effects with this drug: Acute kidney injury. To read a summary of that study click this link to it at the Journal of Oncology Practice.

If you want to read about other potential side effects AND a list of medical conditions that would preclude you from using this drug go to: Aclasta Information: Reclast side effects

If you want more information about this medication and/or if you want to print out material to take with your to your visit with your health care provider,  click on:   Aclasta, Reclast Research Studies

End of Acalsta Osteoporosis information....but if you would like to read comments from those who have used this drug (or if you want to leave a comment on this Aclasta Osteoporosis information page) please scroll down to the very end of this page. 

Other medications for Osteoporosis

Other medications for low bone density can be found at:                                Osteopenia and Osteoporosis medications

If you are interested in learning about the natural treatments for building stronger bones, go to Natural Osteopenia, Osteoporosis Treatments

NOTE: This web site offers science based information, such as the Aclasta infroamtnin given above. The web site does not offer medical advice at any time. For medical advice you need to consult your licensed medical practitioner.

I do offer a FREE monthly newsletter with updates about Osteopenia and Osteoporosis treatments as well as encouragement to women and men with these conditiosn. Click to subscribe to the Osteopenia3 updates newsletter 

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Reader Comments received :

1. From Jeanne in Adelaide South Australia.

SPECIAL NOTE: If you have used Aclasta and would like to leave a comment about your experience, please use the  form below. Please be sure to put the word Aclasta at the beginning of your comment so I know which page you are commenting on. (I use the same form for all pages.) If you do not put Aclasta information or  Zolendronic acid information at the top of your response, I shall not be able to add your comments to this page. Thanks.

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Jean in Adelaide, South Australia Not rated yet
On 23 January 2018 I had my first infusion of Aclasta. I felt fine for around 15 hours afterwards and then developed the flu like symptoms I was warned …

Aclasta reaction Not rated yet
I had aclasta on a Tuesday afternoon that night I started shaking and felt like I had been transported to the Antartic. Muscle pain in the back and legs …

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