Aclasta Osteoporosis information. Aclasta is a drug sold in Europe and Australia. In the United States this drug is distributed under the name Reclast. ( See: Reclast )
Aclasta is a form of zoledronic acid that is administered as an infusion in your doctor's office. Many patients prefer this Osteoporosis medication because they receive this just treatment once a year. (No need to remember daily or weekly pills.) You go to your doctor's office once a year, have your infusion and then you are done til next year.
Osteoporosis treatment with Aclasta (Reclast) appeals to those who prefer to not to have to remember daily or weekly pills. There is nothing to remember with this drug! (Most doctors' office staff are more than willing to keep track of your treatment date and they will give you a call when it is time for you to come in for your annual infusion with Aclasta.
If you are considering Aclasta, you will want to know a bit more about this drug.
Novartis, one of the largest pharmaceutical companies in the world, is the company that makes Aclasta. They developed the drug and did the necessary studies on it.
After study called The Pivotal Fracture Trial showed that Aclasta increased bone strength and it reduced fractures of the hip, spine and other areas such as people's wrists, arms, legs and/or ribs, Aclasta was approved for use by those with documented bone loss.
Please Note: The approval studies showed that Aclasta appeared to be effective in reducing fractures, which is the real reason why anyone would undergo drug treatments for Osteoporosis.
At the time of its approval, they claimed that this was the only treatment that was shown to reduce fractures at ALL the key sites where Osteoporosis fractures usually occur: hips, spine, wrists, arms, legs and ribs.
In addition, for those concerned about the small spinal fractures that can cause dowagers humps, the New England Journal of Medicine reported in May 2007that a study involving more than 7,700 women, showed that treatment with this drug reduced the risk of spinal fractures by 70% (as well as reducing hip fractures by 41%.)
The reduction in spinal fractures for the three years of the study was as follows: 60% reduction in year one; 71% in year two and 70% in year three. Those are significant numbers! - especially when we consider that bone loss in the spine usually lead to kyphosis (or dowagers hump) - a difficult and unsightly condition.
A spokesperson for Novatis, the company manufacturing the drug said in their Aclasta Osteoporosis information that this drug: "has shown significant efficacy in protecting women against fractures in all the common osteoporotic fracture sites, while demonstrating a favorable safety profile, It is our hope that this innovative once-yearly dosing regimen will have a positive impact on the management of this potentially devastating condition."
Novartis also states in the same Aclasta Osteoporosis information that the medication: "is indicated for treatment of osteoporosis in postmenopausal women. In patients with a recent low-trauma hip fracture".. the drug.. "reduces the incidence of new clinical fractures".
If you are considering getting this annual infusion, you may be interested in knowing that Aclasta is:
Other advantages. Many in the health care community believe that once a year infusions are the helpful for patients because they offer a remedy for the inconvenience of daily, weekly or monthly Osteoporosis medications. Also annual infusions eliminate one of the main problems of daily or monthly medications - that many people just stop taking their prescribed medication! (The failure to take medication is called 'non-compliance' by the medical community and it has been shown that Osteoporosis medication non-compliance with daily or weekly pills is high. Aclasta reduces the non-compliance rate.)
Aclasta Osteoporosis information: side effects Since this drug is sold under various names in different countries, the same side effects apply to its other form: Reclast. (In fact, if you live in the United States, the Novartis site will direct you to a page about Reclast.)
Novartis is careful to mention in their Aclasta Osteoporosis information the possibility of developing Osetonecrosis with Aclasta since it is a bisphosphonate drug. . The company also states in its Aclasta information that:
"Disturbances of mineral metabolism must be treated before starting therapy. Patients must be adequately supplemented with calcium and vitamin D. A single dose of Aclasta should not exceed 5 mg and infusion time should be no less than 15 minutes."
Serious side effects: A study published in March of 2013, showed a more serious side effects with this drug: Acute kidney injury. To read a summary of that study click this link to it at the Journal of Oncology Practice.
If you want to read about other potential side effects AND a list of medical conditions that would preclude you from using this drug go to: Aclasta Information: Reclast side effects
If you want more information about this medication and/or if you want to print out material to take with your to your visit with your health care provider, click on: Aclasta, Reclast Research Studies
End of Acalsta Osteoporosis information... If you have used this drug and want to leave a comment about your experience on this Aclasta Osteoporosis information page) please scroll down to the very end and use the form provided. Thanks.
If you are interested in learning about the natural treatments for building stronger bones, go to Natural Osteopenia, Osteoporosis Treatments
NOTE: This web site offers science based information, such as the Aclasta infroamtnin given above. The web site does not offer medical advice at any time. For medical advice you need to consult your licensed medical practitioner.
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Jean in Adelaide, South Australia Not rated yet
On 23 January 2018 I had my first infusion of Aclasta. I felt fine for around 15 hours afterwards and then developed the flu like symptoms I was warned …
Aclasta reaction Not rated yet
I had aclasta on a Tuesday afternoon that night I started shaking and felt like I had been transported to the Antartic. Muscle pain in the back and legs …