Actonel Patient information: Osteopenia, Osteoporosis treatment

 Actonel Patient information: Actonel is the brand name for risedronate sodium a drug that is prescribed for the prevention as well as the treatment of post menopausal Osteoporosis. This drug comes in tablet form.

Since Actonel has been approved for the prevention of Osteoporosis, it is often prescribed for persons with Osteopenia .  It is like Fosamax and Boniva in that it slows the work of your Osteoclast cells.  (Osteoclasts are the cells responsible for removing old bone.)

The drug does not stimulate or have any affect on your Osteblasts, the cells that build new bone. While you take this drug, your osteoblasts continue to make new bone at the same pace as they did before you started taking this medication. BUT since Actonel prevents old bone from being removed so quickly, your bone density   increases. As a result a person with Osteopenia, or thinning bones, is less likely to  progress to Osteoporosis , porous bone, which is a more serious bone loss condition.

Use and dosage. The prescription tablets are manufactured in three different doses 5mg, 30 mg and 35mg. The 5mg tablet is taken each day. The 30mg and 35mg tablets are for once a week use.

The drug has been shown to reduce spinal fractures during the First Year of taking the medication. And it has been shown to be useful to men as well as women.

There was a study of this drug in Japan with men who developed Osteoporosis after having a stroke. The study stated that:

"There is a high incidence of hip fractures in patients after hemiplegic stroke. Bone mineral density is decreased on the hemiplegic side in patients after stroke, correlating with the immobilization-induced bone resorption, the degree of paralysis, and hypovitaminosis D. The purpose of this study is to evaluate the effectiveness of risedronate sodium, an inhibitor of bone resorption, on osteoporosis and the risk of hip fractures in men 65 years or older after stroke."

The study, "Risedronate Sodium Therapy for Prevention of Hip Fracture in Men 65 Years or Older After Stroke" was made by Yoshihiro Sato, MD; Jun Iwamoto, MD; Tomohiro Kanoko, PhD; Kei Satoh, MD It can be found in Arch Intern Medicine 2005;165:1743-1748. If you want to read its conclusions, go to Risendronate sodium (Actonel)

Frequently questions in Actonel Patient Information: Osteopenia, Osteoporosis drug

How should I take this medication?
This medication should be taken in the morning with a full glass of water.

More Actonel patient information about taking this medication: You need to stay upright for at least 30 minutes after taking the tablet. Do not lie down or bend over. Also, do not eat or drink anything for at least 30 minutes. That means you need to wait the full 30 minutes before taking any other medications, vitamins or even your morning coffee.

NOTE: If you lie down before 30 minutes is up, you risk damaging the lining of your stomach. If you eat or drink anything in the same time period, you can reduce the effectiveness of the drug. Be sure to follow your health care provider's instructions about Actonel patient information.

Are there things I should discuss with my health care provider before taking this drug?

Because Risendronate sodium can cause ulceration, you should tell your health care provider if you:

  • have any problem swallowing;
  • have esophageal ulcers or esophageal disease;
  • have stomach ulcers or other stomach problems;
  • can not stand or sit upright for at least 30 minutes in the morning after taking this medication.

Also if you have any condition that causes low levels of calcium in your body or if you have kidney disease be sure to remind your health care professional of these things.

It is not known if this drug will harm a fetus so if you are pregnant or if you can become pregnant, be sure to discuss this with your medical provider. The same is true if you are breast feeding. 

Can I take this drug if I take other prescriptions or over-the-counter medications?
The company notes in their Actonel consumer information that you may need a special dosage.... or you may not be able to use Actonel at all with certain medications. If you take any of the following medications Be sure to discuss them with your health care provider:

  • Antacids
  • Aspirin
  • Nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others)
  • Ketoprofen (Orudis KT, Orudis, Oruvail)
  • Indomethacin (Indocin, Indocin SR)
  • Naproxen (Anaprox, Aleve, Naprosyn)
  • Oxaprozin (Daypro)
  • Nabumetone (Relafen)
  • Piroxicam (Feldene) with your health care provider reviews ALL your medications.

Also it is important to let your health care provider know if you use any herbal products. Some could interfere with Actonel (risendronate sodium) and you many need special dosages.  Note: that it is not usual for Herbal product interactions to be listed in the company's Actonel Consumer information.

Possible side-effects: There are a host of possible negative side effects of Actonel and you can read them here 

More Actonel patient information:  possible good side effects

Yes, there are some potentially good side effects of Actonel - especially if you have Osteoarthritis. A British study of this drug and Osteoarthritis of the knee enrolled patients (40 to 80 years of age) with mild to moderate Osteoarthritis of the medial compartment of the knee.

Results: "Risedronate (15 mg) significantly reduced markers of cartilage degradation and bone resorption (bone loss). Clear trends towards improvement were observed in both joint structure and symptoms in patients with primary knee OA treated with risedronate" (Actonel). If you have Osteoarthritis and Osteopenia or Osteoporosis, you may want to read more Actonel consumer information and/or talk with your physician.

Sources about Actonel patient information: 
RX List -http://www.rxlist.com/cgi/generic/risedronate.htm and Drugs.com -http://www.drugs.com/actonel.html 

Research studies can be found at Actonel Research Results  

Read about other Osteopenia Medications at Osteoporosis Osteopenia medications   Special note: This web site offers science based information, not medical advice. For medical advice you need to consult your licensed medical practitioner for Actonel patient information or information about any other Osteoporosis medication. 


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