Ipriflavone Osteoporosis, Osteopenia
Information about Ipriflavone Osteoporosis, Osteopenia
This is dispensed a pharmaceutical drug in Japan, Italy and several other nations. It has not been approved as a drugIn those countries where there is no Ipriflavone Osteoporosis pharmaceutical drug, some people take it as a natural supplementand it is sold a many health food stores. You can buy it in single doses or you can buy calcium supplementswith Ipriflavone in them.
Can you give me the basic information about using Ipriflavone Osteoporosis or Osteopenia?
- What is ipriflavone?
It is a synthetic isoflavone that appears to inhibit your osteoclasts in the performance of bone resorption. It also appears to stimulate osteoblasts to build more bone. Most of the research about Ipriflavone Osteoporosis has been done in Japan andItaly.
- Has it been shown to be effecting in either preventing or reversing bone loss?
At least one scientific study indicated that 600 mg a day may prevent bone loss and that it may increasebone mass in post menopausal women.
Another study of 474 post menopausal white women with bone mineral density with normal or Osteopenic bone mineraldensity concluded that in dose of 500 mg a day, isoflaone had no significant benefit in bone density or the number of fractures. There was a negative side effect of lymphocytopeni (see: below) in a significant number of the women.
- How much is the normal dose?
Some take 200 mg three times a day; others take 300 mg twice day.
- Are there any side effects?
In a trial where 132 women took ipriflavone over a 3 year period, 29 of the women developed a significant dropin lymphocytes, critical components on the immune system. It took these women almost 2 years before they returnedto normal lymphocytes counts. Any woman taking this drug or supplement, should have her lymphcytes measured on a regularbasis by her physician.
In at least one study it was shown that taking this flavone in addition to estrogen, increase the effect of estrogen in the uterus - thus raising some concern about cancer
It is advised that anyone with kidney disease consult their health care provider before using Ipriflavone. A lower dose is recommended in kidney disease.
The only other side effect reported has been mild stomach upset.
- What about drug interactions?
If you are taking any drug that is metabolized in the liver, such as Theophylline, tolbutamide, Dilantin (phenytoin), Coumadin (warfarin) Ipriflavone might change the levels of that drug in your body.
s noted above, Ipriflavone might also increase the risk of uterine cancer if you are taking estrogen.
YOu should not use this supplement/drug unless under medical supervison if you are taking any drug that suppresses the immune system eg. corticosteroids, methotrexate, or cyclosporine
To read a fuller report about Ipriflavone Osteoporosis, Osteopenia
If you are going to buy Ipriflavone as a supplement you will find that Vitacost offers several types and brands. There is a link to Vitacost on the Osteopenia Products page.
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