Aclasta information: Zolendronic acid for Osteoporosis

Aclasta information. Aclasta is an Osteoporosis drug sold in Europe. In the United states it is distributed under the name Reclast. ( If you wish to read the pages about the USA form, just click on Reclast )

Both of these are forms of zoledronic acid, an Osteoporosis drug that is taken just once a year.  The drug is given by an infusion in your doctor's office. (Note: no pills)

Many people really like having their Osteoporosis treatment only once a year. No need to remember daily or weekly pills. With Aclasta (Reclast) you only need to go to your health care provider's office once a year for your Osteoporosis treatment.

This osteoporosis drug appeals to the many people who really like not having to remember  daily or weekly pills. There is nothing to remember with this drug! Most doctors' office staff are more than willing to keep track and give you a call when it is time for you to come in for your annual infusion.

More Aclassta information. If you are considering Aclasta, you will want to know a bit more about this particular Osteoporosis drug. . You especially want to find out if there is anything that could pose a problem for you so read on to gt more Acasta information.

Novartis is the drug company that manufactures Aclasta

Novartis is one of the largest pharmaceutical companies in the world.  After a  three year study called Pivotal Fracture Trial showed that Aclast increased bone strength and it reduced fractures of the hip, spine and other areas such as people's wrists, arms, legs and/or ribs, the drug was approved for use. Note: There is a claim  that this treatment is the only treatment that has been shown to reduce fractures at ALL the key sites where Osteoporosic fractures usually occur: hips, spine, wrists, arms, legs and ribs. That is important Aclasta information. This drug appears to be effective in reducing fractures.

As for the small spinal fractures that often cause dowagers humps, you may want to know that in May 2007 the New England Journal of Medicine reported that a study involving more than 7,700 women showed that treatment with this drug reduced the risk of spinal fractures by 70%  and the drug reduced hip fractures by 41%.

The reduction in spinal fractures for the three years of the study was as follows: 60% in year one; 71% in year two and 70% in year three.  Again, those are significant numbers! - especially when we consider that bone loss in the spine usually lead to kyphosis (or dowagers hump)  - a difficult and unsightly condition. 

More Aclasta information:

To read more about this medication and/or to print out material to take with your to your health care provider,  go to:  Aclasta, Reclast Research Studies

NOTE: A spokesperson for Novatis said this drug: "has shown significant efficacy in protecting women against fractures in all the common osteoporotic fracture sites, while demonstrating a favorable safety profile, It is our hope that this innovative once-yearly dosing regimen will have a positive impact on the management of this potentially devastating condition." 

Novartis states that this medication:

   "is indicated for treatment of osteoporosis in postmenopausal women. In patients with a recent low-trauma hip fracture," the drug "reduces the incidence of new clinical fractures". And it is:

  • "indicated for treatment of osteoporosis in men at increased risk of fracture, including those with a recent low-trauma hip fracture."
  • "indicated for treatment of osteoporosis associated with long-term systemic glucocorticoid therapy in postmenopausal women and in men with increased risk of fracture".
  • and finally, "Aclasta is indicated for the treatment of Paget's disease of the bone."

Many in the health care community believe that once a year infusions are an effective remedy for the inconvenience of daily, weekly or monthly Osteoporosis medications. The main problem with daily or even monthly medications is that many people just stop taking their prescribed medication for Osteopenia and Osteoporosis! (This failure to take one's medication is called 'non-compliance' by the medical community and it has been shown that non-compliance with daily or weekly pills for bone loss is high.)

More Alcasta information: side effects

Aclasta information: side effects Since this drug is sold under various names in different countries, the same side effects would apply  under its other name, Reclast. In fact, if you live in the United States, the Novartis site directs your to a  page about Reclast.

Novartis is careful to mention in their Aclasta information the possibility of developing Osetonecrosis with any of the bisphosphonates (of which Aclasta is one). The company also states in its Aclasta information nptoces that:

"Disturbances of mineral metabolism must be treated before starting therapy. Patients must be adequately supplemented with calcium and vitamin D. A single dose of Aclasta should not exceed 5 mg and infusion time should be no less than 15 minutes."

A study published in March of 2013, showed amore serious side effects with this drug: Acute kidney injury. You can read a summary of that study by clicking this link to the Journal of Oncology Practice.

If you want to read about other potential side effects and a list of conditions that would preclude using this drug go to: Aclasta Information: Reclast side effects

End of Acalsta information.

Other medications for Osteoporosis

Other medications for low bone density can be found at:                              Osteopenia and Osteoporosis medications

If you are interested in learning about the natural treatments for building stronger bones, go to Natural Osteopenia, Osteoporosis Treatments

NOTE: This web site offers science based information, such as the Aclasta infroamtnin given above. The web site does not offer medical advice at any time. For medical advice you need to consult your licensed medical practitioner.

I do offer a FREE monthly newsletter with updates about Osteopenia and Osteoporosis treatments as well as encouragement to women and men with these conditiosn. Click to subscribe to the Osteopenia3 updates newsletter 

  Go  to: HOME 

Reader Comments received :

1. From Jeanne in Adelaide South Australia.

SPECIAL NOTE: If you have used Aclasta and would like to leave a comment about your experience, please use the Testimonial form below. Please put the word Aclasta at the opening of your comments so I know what your comments are about. (I use the same form for all pages.) If you do not put Aclasta inforamtion or  Zolendronic acid information at the top of your response, I shall not be able to add your comments to this page. Thanks.

Have you experience with this?

Do you have experience with this? Please share it!

[ ? ]

Upload 1-4 Pictures or Graphics (optional)[ ? ]


Click here to upload more images (optional)

Author Information (optional)

To receive credit as the author, enter your information below.

(first or full name)

(e.g., City, State, Country)

Submit Your Contribution

 submission guidelines.

(You can preview and edit on the next page)

What Other Visitors Have Said

Click below to see contributions from other visitors to this page...

Jean in Adelaide, South Australia Not rated yet
On 23 January 2018 I had my first infusion of Aclasta. I felt fine for around 15 hours afterwards and then developed the flu like symptoms I was warned …

Aclasta reaction Not rated yet
I had aclasta on a Tuesday afternoon that night I started shaking and felt like I had been transported to the Antartic. Muscle pain in the back and legs …

Click here to write your own.