Dr. Fujita's Advacal research results This calcium was the first one I found that offered research about its effectiveness.
because Dr. Fujita was a real scientist, his Advacal research studies were real scienfitic
studies. They were published in scientific journals. They were not just 'in
house' studies listed in some advertisements for other Osteoporosis products.
Perhaps it would helpful
to allow Dr. Fujita to speak about AAA Ca (Advacal) himself. Here are
some abstracts from his studies:
The first Advacal research study outlined the reasons why the studies are so important:
- Osteoporosis International . 1997;7 Suppl 3:S6-9.
"Osteoporosis is an old and continuing problem which has
been a challenge to medical research and care throughout the history of
mankind. After the break-through with estrogen, many new agents as
well as nutritional and physical interventions were found to be
effective in preventing and controlling osteoporosis.
Calcium represents one of the keys to all these methods,
especially with the appearance of new highly biologically available
forms influencing cell calcium metabolism. It appears to be important to
focus our attention not only on the physical properties and strength of
bone but also on its calcium storage function. By controlling
osteoporosis and restoring the proper calcium storage function of the
bone, many diseases of old age which are due to or exacerbated by
calcium deficiency and disturbed calcium distribution in the body, such
as hypertension, arteriosclerosis and senile dementia, may also be
- The second Advacal research study outlined some of
the differences between the situation in Japan and the United States
These differences explain in some of the reasons why T.
Fujita and his colleagues have spent so much time studying forms of
calcium, while researchers elsewhere have concentrated on the
effectiveness of hormone replacement therapy and pharmaceutical drugs:
"In Japan, unlike in the United States and Europe, where
osteoporosis is synonymous with postmenopausal osteoporosis, the need
for treatment of osteoporosis has been emphasized only for elderly women
with established disease.
This may be because women in the immediate
postmenopausal period in Japan are virtually free of symptoms such as
lumbago and signs such as spinal compression fracture. Osteoporosis
typically does not manifest itself until about age 65; therefore,
postmenopausal osteoporosis with vertebral fracture below the age
is quite rare in Japan.
Unique features of treatment for osteoporosis in Japan include
rare use of estrogen replacement therapy, common use of vitamin D
derivatives (especially 1alpha(OH) vitamin D) without notable side
effects, and use of calcitonin almost exclusively in a low-dose
intermittent regimen (20 U/week). Similarly, the use of ipriflavone is
common, and calcium supplementation, especially with an active
absorbable algae calcium with high bioavailability (AAACa), is effective
The emphasis on the use of calcium, vitamin D, and calcitonin in
the treatment of osteoporosis may be explained by an extremely low
dietary calcium intake in
factors that favor reliance on
the calcium-focused approach and avoidance of estrogen include a
fatalistic and naturalistic view toward menopause; an uneasiness with
hormone replacement therapy; an older female population who seek
osteoporosis treatment because of uneventful immediate postmenopausal
periods; and the efficient absorption of calcium from the intestine with
favorable response to exogenous vitamin D due to a long-standing
calcium deficiency and possibly a low incidence of vitamin D-receptor
abnormalities." It used to be somewhat of a truism that the older you are, the more difficult it is to increase bone density.
But Fujita's Advacal research studies have challenged that assumption.
If these Advacal research studies convince you to try this calcium supplement,
you can order Advacal Ultra with Magnesium, Vitamin D and now a form with Vitamin K directly from
the company that makes this product, Lane Labs. Here is a link to their
web site at Compassion Net. Advacal and other products by Lane Labs
- Another Advacal research study was done on hospitalized 80 year olds
(Since they are hopsitalized they are certainly not doing 'bone density
exercises"!). I know the abstract is long but it worth taking the time
to really read it since the results are important for us to understand.
Calcif Tissue Int. 1996 Apr;58(4):226-30by Fujita T, Ohue T,
Fujii Y, Miyauchi A, Takagi Y. Calcium Research Institute, Osaka, Japan.
"A randomized, prospective, double-blind test was carried out to
compare the effects of heated oyster shell-seaweed calcium (AAA Ca),
calcium carbonate, and placebo in 58 elderly, hospitalized women with
the mean age of 80 divided into three groups.
Group A received 900 mg/day Ca as AAA Ca, Group B 900 mg/day Ca
as CaCO3, and Group C placebo besides regular hospital diet containing
approximately 600 mg Ca/day for 24 months. From the 25th to the 30th
month, all groups were given AAA Ca.
Lumbar spine and radial bone mineral density (BMD) were measured
at 3-month intervals. Urinary Ca/Cr and serum alkaline phosphatase,
intact and midportion serum parathyroid hormone (PTH), and calcitonin
were also measured at intervals.
From the 6th to the 24th month of the study, the ratio of lumbar
spine BMD (L2-L4 by DPX, Lunar) to the basal pretest value was
consistently and significantly higher in Group A than Group C but not
higher in Group B than in Group C. PTH, measured 12 months after the
beginning of the study, was lower in Group A than in Group C, but no
significant difference was found between Groups B and C.
At 3 months after the placebo was switched to AAA Ca in Group C,
serum PTH was significantly decreased from the level during placebo
supplement. Morning urine Ca/Cr decreased in Groups A after 18 months
and in B after 12 months, but not in C. Serum alkaline phosphatase
decreased in Group A significantly compared with Group C, but not in
Group B. AAA Ca appears to be effective for increasing BMD in elderly
(Note the carefulness of the concluding sentence! No hyped up advertising language in these studies.)
SOURCES: All this information came from Pub Med an on-line database of published scientific studies.
A bit of advice about taking calcium supplements
Remember that you should always take your calcium supplements with food.
It is most effective to divide your daily dose and
take some of your calcium before bedtime since this will counter the night time activity of your para
So, if you are using Advacal, take one dose in the
morning and the other at night.
You will find Advacal in both the regular and Ultra AND they now
offer a form with Vitamin K - useful for those concerned about calicium
supplements and heart disease.
Buy some at: Lane Labs: Compassion Net.
Read more about Advacal research studies